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How Is The Bond Created? When two amino acids form a covalent bond, it creates a peptide bond.[1] The Carboxyl group of one amino acid may react with the second amino group of the other amino acid. This essentially forms a peptide bond. Due to this process, a molecule (amide) filled with water may be […]
How To Find The Best Peptide Solubility Option Figuring out the most effective solvent to dissolve peptides with is possibly one of the most difficult components when working with peptides and conducting research. Aqueous solutions–also known as sterile waters–are one way to dissolve peptides. Problems do, however, still arise with this method. Some issues you may […]
Here you will find information on the different aspects of peptide purification that take place during the synthesis, different strategies and methods, and possible mistakes, such as impurities that may actually be removed by purification during the synthesis. Peptides are unique and complex. Due to this complexity, they can affect purification methods that work for […]
The Process of Peptide Synthesis Solution Phase Synthesis (SPS) was the original approach to peptide synthesis. Though this process still has merit in this modern age, for large-scale peptide production, Solid-Phase Peptide Synthesis (SPPS) has become to be the method of choice of most scientists. SPPS’s advantages are the reason for this. SPPS appears to […]
Long-term peptide storage over several months and years demands proper refrigeration. The preferred and usual temperature for storage is -80C (-112F). Freezing peptides is optimal to preserve their stability and retain functional viability. Peptides are short stretches of amino acids that mimic their full-length counterparts’ functions. They can be natural or synthetic and find research […]